Quinolines and derivatives
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Filtered Search Results
Medchemexpress LLC PEG-bis-amine (MW 20000) | 24991-53-5 | 98.0% | (C2H4O)nC4H12N2O | 250 MG
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PEG-bis-amine (Poly(ethylene glycol)-bis-amine) (MW 20000) is a PEG-based PROTAC linker designed for the synthesis of PROTACs. These molecules employ the intracellular ubiquitin-proteasome system to selectively degrade target proteins by connecting two ligands: one for an E3 ubiquitin ligase and another for the target protein. This compound appears as a white to off-white solid and has an average molecular weight of 20000. It is intended for research use only.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- White to off-white solid appearance
- Average molecular weight of 20000
- Purity of 98.0%
- Soluble in water at 100 mg/mL (requires ultrasonic)
- Stable as powder at -20°C for 3 years
- Stable in solvent at -80°C for 6 months or -20°C for 1 month
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Medchemexpress LLC Mpeg-amine (MW 1000) | 80506-64-5 | 99.19% | (C2H4O)nC3H9NO | 100 MG
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m-PEG-NH2 (MW 1000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Facilitates degradation of target proteins
- Utilizes the ubiquitin-proteasome system
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Medchemexpress LLC Quin C1 | 786706-21-6 | 98.5% | 445.51 | 25 MG
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Quin C1 is a highly specific and potent agonist for formyl peptide receptor 2 (FPR2/ALX). Quin-C1 significantly reduces the neutrophil and lymphocyte counts in BALF, diminishes expression of TNF-α, IL-1β, KC, and TGF-β1, and decreases collagen deposition in lung tissue. Quin C1 has the potential for the research of lung injury.
- Highly specific and potent agonist for formyl peptide receptor 2 (FPR2/ALX).
- Significantly reduces neutrophil and lymphocyte counts in BALF.
- Diminishes expression of TNF-α, IL-1β, KC, and TGF-β1.
- Decreases collagen deposition in lung tissue.
- Potential for research of lung injury.
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Medchemexpress LLC Amino-PEG8-amine | 82209-36-7 | ≥98.0% | 250 MG
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Amino-PEG8-amine is a PEG-based (8 units) PROTAC linker used in the synthesis of PROTACs. PROTACs, or Proteolysis-targeting chimeras, consist of two different ligands connected by a linker. One ligand targets an E3 ubiquitin ligase, and the other targets the protein of interest. PROTACs utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based (8 units) linker
- Can be used in the synthesis of PROTACs
- Ligands connected by a linker target E3 ubiquitin ligase and protein of interest
- Utilizes intracellular ubiquitin-proteasome system to selectively degrade target proteins
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eMolecules 2246-44-8 | 2-Methylnaphthalen-1-amine | Ambeed | MFCD00059135 | 157.216 | C11H11N | 95.000 | Cc1ccc2ccccc2c1N | 5g | 528570193
2-Methylnaphthalen-1-amine | Ambeed | 2246-44-8 | MFCD00059135 | 157.216 | C11H11N | 95.000 | Cc1ccc2ccccc2c1N | 5g | 528570193
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Medchemexpress LLC Azido-PEG10-amine | 912849-73-1 | MFCD03453246 | ≥97.0% | C22H46N4O10 | 5 G
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Azido-PEG10-amine is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an Azide group that allows it to participate in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions. PROTACs themselves are designed to exploit the intracellular ubiquitin-proteasome system for the selective degradation of target proteins.
- Functions as a click chemistry reagent
- Contains an azide group
- Participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions
- Engages in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
- Utilized in the synthesis of PROTACs
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eMolecules 58794-09-5 | 7-bromoisoquinoline | AA Blocks LLC | MFCD07368661 | 208.058 | C9H6BrN | 0.000 | Brc1ccc2ccncc2c1 | 2g | 795063184
7-bromoisoquinoline | AA Blocks LLC | 58794-09-5 | MFCD07368661 | 208.058 | C9H6BrN | 0.000 | Brc1ccc2ccncc2c1 | 2g | 795063184
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Aobchem 7-Bromoisoquinoline | ≥95% | CAS 58794-09-5 | C9H6BrN | 1g
7-Bromoisoquinoline | ≥95% | CAS 58794-09-5 | C9H6BrN | 1g
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Aobchem 5-Bromoquinoline | ≥95% | CAS 4964-71-0 | C9H6BrN | 25g
5-Bromoquinoline | ≥95% | CAS 4964-71-0 | C9H6BrN | 25g
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Aobchem 1-(Quinolin-6-yl)ethanol | ≥95% | CAS 638191-97-6 | C11H11NO | 250mg
1-(Quinolin-6-yl)ethanol | ≥95% | CAS 638191-97-6 | C11H11NO | 250mg
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eMolecules 5622-36-6 | methyl 2-(quinolin-6-yl)acetate | Pharmablock - Stock | MFCD04038669 | 201.225 | C12H11NO2 | 97.000 | COC(=O)Cc1ccc2ncccc2c1 | 5g | 415696919
methyl 2-(quinolin-6-yl)acetate | Pharmablock - Stock | 5622-36-6 | MFCD04038669 | 201.225 | C12H11NO2 | 97.000 | COC(=O)Cc1ccc2ncccc2c1 | 5g | 415696919
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Medchemexpress LLC Amino-PEG8-amine | 82209-36-7 | 98.0% | 5 G
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Amino-PEG8-amine is a PEG-based (8 units) PROTAC linker that is used in the synthesis of PROTACs. PROTACs are compounds that contain two different ligands connected by a linker; one ligand is for an E3 ubiquitin ligase and the other is for the target protein. These PROTACs leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PROTACs contain two different ligands connected by a linker.
- One ligand is for an E3 ubiquitin ligase.
- The other ligand is for the target protein.
- They exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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Medchemexpress LLC Mal-amido-PEG9-amine (TFA) | 2569576-12-9 | 99.4% | C27H49N3O12.C2HF3O2 | 10MG
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Mal-amido-PEG9-amine (TFA) is a PEG-based PROTAC linker that contains a maleimide moiety and a terminal amine present as the trifluoroacetic acid salt. It is designed as a hydrophilic spacer to connect ligands in bifunctional molecules and to enable selective thiol conjugation while providing an amine handle for further coupling reactions.
- Maleimide group enables selective thiol conjugation.
- Terminal amine (TFA salt) provides an amide-coupling handle.
- PEG9 spacer increases solubility and molecular flexibility.
- Suitable for assembly of bifunctional molecules such as PROTACs and bioconjugates.
- Available in small mg-scale quantities for research use.
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Medchemexpress LLC 8-Aminoquinoline | 578-66-5 | 144.17 | 100 G
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8-Aminoquinoline is a biochemical reagent suitable for life science related research. It can be used as a biological material or organic compound, and is intended for research use only.
- Biochemical reagent
- Can be used as biological material
- Can be used as organic compound
- Suitable for life science related research
- Functions as an inhibitor
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eMolecules 58794-09-5 | 7-Bromoisoquinoline | Oakwood Chemicals | MFCD07368661 | 208.058 | C9H6BrN | 0.000 | Brc1ccc2ccncc2c1 | 250mg | 480128099
7-Bromoisoquinoline | Oakwood Chemicals | 58794-09-5 | MFCD07368661 | 208.058 | C9H6BrN | 0.000 | Brc1ccc2ccncc2c1 | 250mg | 480128099
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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