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Filtered Search Results
Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000266535 EDOXABAN IMPURITY 59 25MG
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![eMolecules 56-57-5 | 4-Nitroquinoline n-oxide | Combi-Blocks | MFCD00006738 | 190.158 | C9H6N2O3 | 98.000 | [O-][N+](=O)c1cc[n+]([O-])c2ccccc12 | 1g | 303330926](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000492596.jpg-250.jpg)
eMolecules 56-57-5 | 4-Nitroquinoline n-oxide | Combi-Blocks | MFCD00006738 | 190.158 | C9H6N2O3 | 98.000 | [O-][N+](=O)c1cc[n+]([O-])c2ccccc12 | 1g | 303330926
4-Nitroquinoline n-oxide | Combi-Blocks | 56-57-5 | MFCD00006738 | 190.158 | C9H6N2O3 | 98.000 | [O-][N+](=O)c1cc[n+]([O-])c2ccccc12 | 1g | 303330926
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Medchemexpress LLC Quinine hydrochloride dihydrate | 6119-47-7 | 99.7% | 5 G
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Quinine hydrochloride dihydrate is an orally active anti-malarial agent that functions as a potassium channel inhibitor. It has demonstrated inhibitory effects on WT mouse Slo3 (KCa5.1) channel currents and on the proliferation and cytostatic effects of Dengue virus (DENV) in human hepatocarcinoma HepG2 cells. Additionally, it has shown some tumor-suppressing effects on skin cancer in Swiss albino mice.
- Acts as a potassium channel inhibitor
- Inhibits WT mouse Slo3 (KCa5.1) channel currents
- Inhibits Dengue virus proliferation and cytostatic effects in HepG2 cells
- Reduces viral DENV RNA and protein levels
- Shows tumor-suppressing effects on skin cancer
- Molecular weight: 396.91
- Appearance: white to off-white solid
- In vitro solubility: soluble in DMSO (≥ 100 mg/mL) and H2O (20 mg/mL)
- For research use only
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000760476 6-BROMOHEXAN-1-AMINE 5G
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![eMolecules 56-57-5 | 4-Nitroquinoline n-oxide | Combi-Blocks | MFCD00006738 | 190.158 | C9H6N2O3 | 98.000 | [O-][N+](=O)c1cc[n+]([O-])c2ccccc12 | 5g | 335368515](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000492416.jpg-250.jpg)
eMolecules 56-57-5 | 4-Nitroquinoline n-oxide | Combi-Blocks | MFCD00006738 | 190.158 | C9H6N2O3 | 98.000 | [O-][N+](=O)c1cc[n+]([O-])c2ccccc12 | 5g | 335368515
4-Nitroquinoline n-oxide | Combi-Blocks | 56-57-5 | MFCD00006738 | 190.158 | C9H6N2O3 | 98.000 | [O-][N+](=O)c1cc[n+]([O-])c2ccccc12 | 5g | 335368515
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Medchemexpress LLC Mebendazole-amine 5mg | 52329-60-9 | 237.26 g/mol | C14H11N3O | 5 MG
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Mebendazole-amine is a research metabolite of mebendazole supplied as a high-purity solid for analytical and metabolic studies. Store protected from light and follow solvent storage recommendations for long-term stability.
- Research metabolite of mebendazole.
- High purity: 98.35%.
- Molecular weight 237.26 g/mol; formula C14H11N3O.
- Supplied in small vials suitable for analytical work (e.g., 5 mg).
- Appearance: solid, white to off-white.
- Storage: 4°C, protect from light; in solvent, -80°C up to 6 months or -20°C up to 1 month.
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Medchemexpress LLC Navitoclax (ABT-263) | 923564-51-6 | MFCD12756219 | ≥98.0% | 974.61 g·mol⁻¹ | C47H55ClF3N5O6S3 | 200 MG
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Navitoclax (ABT-263) is a potent, orally active small-molecule inhibitor of anti-apoptotic Bcl-2 family proteins used in preclinical apoptosis and oncology research. Supplied as a powder, it is used for both in vitro assays and in vivo models, with documented solubility and recommended storage for stability.
- Potent Bcl-2 family inhibitor for apoptosis research.
- Orally active small molecule suitable for in vivo studies.
- High solubility in DMSO for convenient stock solutions.
- Available in multiple quantities for dosing flexibility.
- Recommended storage conditions to preserve stability.
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Medchemexpress LLC N-allyl-6-bromoquinazolin-4-amine | 307538-42-7 | MFCD02166825 | 99.9% | 264.12 | C11H10BrN3 | 200 MG
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SMER28 is a small-molecule positive regulator of autophagy that operates via an mTOR-independent mechanism and has been reported to reduce accumulation of amyloid beta peptide. It is supplied as a research reagent in solid and solution forms for use in cellular and biochemical studies.
- Positive regulator of autophagy via an mTOR-independent pathway.
- Reported to prevent accumulation of amyloid beta peptide.
- Suitable for in vitro cellular and biochemical autophagy studies.
- Available in multiple package formats including solid and DMSO solution for assay flexibility.
- Characterized by a defined molecular formula and molecular weight for reproducible experiments.
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Medchemexpress LLC Bromocriptine mesylate | 22260-51-1 | 99.90% | 1 ML
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Bromocriptine mesylate is a potent dopamine D2/D3 receptor agonist that readily crosses the blood-brain barrier. It stimulates [35S]-GTPγS binding at the D2 dopamine receptor expressed in CHO cells with a pEC50 of 8.15±0.05. It also acts as a strong inhibitor of brain nitric oxide synthase and a potent inhibitor of CYP3A4.
- It is a potent dopamine D2/D3 receptor agonist.
- It is permeable to the blood-brain barrier.
- It shows significant anti-immobility action in experimental models of depression.
- It induces a significant, dose-dependent decrease in pain scores in specific models.
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Medchemexpress LLC Amine-PEG3-desthiobiotin | 2237234-71-6 | 99.9% | C18H36N4O5 | 10MG
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Amine-PEG3-Desthiobiotin is a PEG-based bifunctional linker combining a short PEG3 spacer, a terminal primary amine, and a desthiobiotin affinity tag. It is designed for PROTAC assembly, bioconjugation, and affinity-capture workflows where reversible binding to streptavidin/avidin aids purification and enrichment.
- Terminal primary amine for efficient coupling to carboxyl or activated ester functionalities.
- Desthiobiotin tag enables reversible affinity capture with streptavidin/avidin systems.
- PEG3 spacer improves solubility and reduces steric hindrance between binding partners.
- High chemical purity suitable for synthetic and analytical applications.
- Available in multiple small-scale quantities to support method development and optimization.
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Apexbio Technology LLC Batimastat (BB-94)(Synonyms: BB-94, Batimastat, MMP inhibitor BB-94), 10mg, CAS: 130370-60-4.
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Batimastat (BB-94 CAS 130370-60-4) is a synthetic small-molecule inhibitor targeting matrix metalloproteinases (MMPs) Structurally a polypeptide-like analogue of collagen substrates batimastat contains a peptidic backbone and a hydroxamate moiety that binds the catalytic zinc atom of MMPs It inhibits several MMP subtypes markedly including MMP-1 MMP-2 MMP-3 MMP-7 and MMP-9 with reported IC50 values of 3 4 20 6 and 4 nM respectively In preclinical studies batimastat demonstrates inhibitory effects on tumor growth and angiogenesis across various tumor models including ovarian and colon carcinoma xenografts making it relevant for cancer research and therapeutic development
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eMolecules 74124-79-1 | N,N'-Disuccinimidyl carbonate | Chem-Impex | MFCD00009767 | 256.170 | C9H8N2O7 | 99.000 | O=C(ON1C(=O)CCC1=O)ON1C(=O)CCC1=O | 1kg | 112443065
N,N'-Disuccinimidyl carbonate | Chem-Impex | 74124-79-1 | MFCD00009767 | 256.170 | C9H8N2O7 | 99.000 | O=C(ON1C(=O)CCC1=O)ON1C(=O)CCC1=O | 1kg | 112443065
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Apexbio Technology LLC Evacetrapib (LY2484595) 1186486-62-3 200mg
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Evacetrapib (LY2484595 CAS 1186486-62-3) is a potent and selective inhibitor targeting cholesteryl ester transfer protein (CETP) a regulator of lipid metabolism Evacetrapib exhibits inhibitory activity with IC50 values of 5 5 nM in assays containing recombinant human CETP and 26 nM within human plasma CETP assays In vivo oral administration at 30 mg/kg in human CETP/ApoAI double-transgenic mice significantly reduces CETP activity and elevates HDL-cholesterol concentration (ED50 5 mg/kg) Evacetrapib does not elevate blood pressure nor induce aldosterone or cortisol synthesis in model systems highlighting its potential in cardiovascular research related to coronary artery disease
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000692238 IMIQUIMOD MALEATE 10MM/1ML
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eMolecules 288154-18-7 | tert-Butyl 4-amino-4-carbamoylpiperidine-1-carboxylate | Combi-Blocks | MFCD04114477 | 243.307 | C11H21N3O3 | 98.000 | CC(C)(C)OC(=O)N1CCC(N)(CC1)C(N)=O | 10g | 517028767
tert-Butyl 4-amino-4-carbamoylpiperidine-1-carboxylate | Combi-Blocks | 288154-18-7 | MFCD04114477 | 243.307 | C11H21N3O3 | 98.000 | CC(C)(C)OC(=O)N1CCC(N)(CC1)C(N)=O | 10g | 517028767
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